Quick facts
FDA-Approved — HIV-Associated Lipodystrophy
Phase 3 Complete
What is Tesamorelin?
Tesamorelin is an FDA-approved medication that acts like the natural signal your brain uses to tell your body to make growth hormone. It has a special structural change that protects it from being broken down too quickly in the bloodstream. Tesamorelin is specifically FDA-approved to reduce excess visceral fat—the hard belly fat that wraps around internal organs—in HIV patients with a specific metabolic condition.
Common Uses
Tesamorelin is FDA-approved for the reduction of excess abdominal fat in HIV-infected patients with lipodystrophy, with Phase 3 trials demonstrating significant results.
Research suggests tesamorelin acts on the pituitary gland to stimulate natural growth hormone release, supporting metabolic function.
Research has explored tesamorelin for potential effects on cognitive function and memory in older adults with mild cognitive impairment.
In clinical trials, tesamorelin was associated with potential improvements in lipid profiles and metabolic markers through growth hormone pathway activation.
Studies & Clinical Research
Everything you need to know about how therapeutic peptides work, how they are made, their safety and legal status, and the eight
Tesamorelin acts like a natural brain signal to tell the body to release growth hormone. Tesamorelin is specifically FDA-approved for reducing visceral fat in HIV patients with lipodystrophy, and research has explored its broader metabolic effects.
Tesamorelin is FDA-approved and was generally well-tolerated in large Phase 3 clinical trials. Common side effects include injection site reactions, fluid retention, and joint pain. A licensed provider can help decide if tesamorelin is appropriate for you.
In clinical trials, tesamorelin was associated with significant reductions in visceral fat over 26 to 52 weeks of treatment. Consistent use is required to maintain results.
Yes. Tesamorelin is a prescription-only, FDA-approved medication. A licensed healthcare provider must review your health history before prescribing tesamorelin.
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